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Why do research here?

Evelina London Children’s Hospital is a research active specialist paediatric heath service with a strong track record of conducting clinical research.

We are the UK’s leading hospital for paediatric cardiology as well as specialists in kidney transplants and dialysis, cleft lip surgery, metabolic conditions, allergy and neurology. 

Evelina London Children’s Hospital is part of Guy’s and St Thomas’ NHS Foundation Trust – one of the most consistently high recruiting sites in England for NIHR portfolio studies. Our research portfolio ranges from babies in the womb, through to young adulthood and transition to adult services.

Our researchers

Our clinicians are chief investigators (CI), principal investigators (PI) and sub-investigators (SI) for a diverse portfolio of commercial and non-commercial studies. We support both National Institute of Health Research (NIHR) portfolios and non-portfolio studies. Many of our investigators are holders of major national and European grants.

Our research portfolio

Our research portfolio includes:

  • clinical trials of investigational medicinal product (CTIMP) – phase I to IV
  • clinical trials of medical devices
  • interventional studies
  • cohort, longitudinal and observational studies
  • registries
  • epidemiological studies
  • qualitative research.

Find out more

Research opportunities

Evelina London is currently looking to expand our research portfolio in the areas of:

  • clinical genetics
  • endocrinology – obesity and diabetes (Type 1 and 2)
  • allied health – physiotherapy and rehabilitation
  • rheumatology
  • infectious disease
  • respiratory – including asthma

In December 2014, the South London-based Genomics Network Alliance, which is led by Guys and St Thomas’, was announced as the successful bidder in the race to become a pioneering Genomic Medicine Centre - part of the groundbreaking 100,000 Genomes Project. This success will expand the ability of the clinical genetics service to conduct research in the area of genetics.

In 2014 Evelina London Children’s Hospital merged its clinical services with children’s community services its – expanding the ability Evelina London to support community-based research. Further opportunities will be available in this area soon.     

If you would like to discuss research opportunities at Evelina London Children’s Hospital, please contact us at evelinaresearch@gstt.nhs.uk

Research areas

All of our services at Evelina London are actively engaged with research. This helps us to provide research opportunities from in vitro to transition to adult services. These include, but are not limited to:

  • accident and emergency (A&E)
  • the Centre for the Developing Brain – neonatal research facility operating in collaboration with King’s College London (KCL)
  • cleft lip and palate
  • cardiology
  • clinical genetics
  • neonatal intensive care (NICU)
  • paediatric intensive care unit (PICU)
  • South Thames Retrieval Service (STRS) – children's acute transport service
  • nephrology
  • allergy and immunology
  • neurosciences
  • general paediatrics
  • Centre for Inherited Metabolic Disease
  • infectious disease
  • non-malignant haematology – sickle cell, thalassaemia, haemophilia and thrombosis
  • rheumatology
  • dentistry and orthodontics

 If you are interested in conducting research in any of our services please feel free to contact us at evelinaresearch@gstt.nhs.uk

If you would like to know more about our consultants and their research interests, please refer to our consultant profiles.

Our community

Evelina London Children’s Hospital draws it’s clinical and research population from south London and the south east of England.

Our three local boroughs – Lambeth, Southwark and Lewisham – are some of the most culturally diverse populations in England with levels of deprivation higher than the national average. 42% of the population of Lambeth are from ethnic minorities and over 150 languages are spoken within the borough.

The diversity and size of our community gives researchers access to a statistically diverse and data rich research population. 

You can see the area of service of both Evelina London Children’s Hospital and South Thames Retrieval Service (STRS) on this map.

STRS works with our neonatal and paediatric intensive care units (NICU and PICU) to safely retrieve critically ill children from the south east of England and deliver them for care at Evelina London.

Local health issues

Our local boroughs of Lambeth, Southwark and Lewisham are all identified as having more diverse health outcomes than the England average.

The communities have a higher rate of obesity in children aged 10 to 11 years old than the average for England. Tackling obesity is a common health objective for the three boroughs.

Other local health priorities include:

  • mental and emotional wellbeing
  • preventing long term conditions through reducing risk
  • lifestyle and behaviour change
  • HIV and sexual health
  • early intervention in children and young people
  • alcohol and smoking

We strongly encourage research that addresses these issues.

Our achievements

2013: we enrolled the first global recruit for GW Pharmaceuticals’ Phase three Paediatric Investigational Plan (PIP) for their new anti-spasticity medication – Sativex® . We continue to recruit to this study and have surpassed our original recruitment target.

2014: the Department of Health announced the appointment of a consortium comprising the University of Leeds and Guy's and St Thomas' NHS Foundation Trust to provide a single National Institute for Health Research (NIHR) Clinical Research Network Coordinating Centre (CRNCC) for the next five years (April 2015 to March 2020). As part of this coordinating centre, we are well placed to respond to feasibility requests for portfolio-adopted studies in a timely manner and the embedding of research delivery into our clinical services. 

 

Contacts

If you are interested in conducting research in any of our services, please contact us at evelinaresearch@gstt.nhs.uk
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